Mac (Seth Rogen) and Kelly (Rose Byrne) are the proud parents of a little girl, somehow resigned to the fact that the wild parties are over for them and that the only spanks they have are the ones on their stomachs. They live in a cozy little house on a quiet street and are slowly preparing for their mid-life crisis.
When the house next door is rented by college kids, led by the sculpted hunk Teddy (Zac Efron), they smell danger, but initially decide to take a friendly approach, which includes a promise to keep the peace at night and a commitment not to call the cops right away if things ever go a little wrong with the partying.
However, the second nighttime drive shatters all noble commitments and an open war between the two houses rages, in which all guns are allowed. At first glance, it might seem that the tired parents don't stand a chance against the rambunctious students, but Mac and Kelly were party people "once upon a time" and remember a lot of pretty nasty tricks from that era...
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