Pongo, a handsome and intelligent Dalmatian, lives in London. On a walk with his master, he meets the beautiful Dalmatian Perdita and falls in love with her. Fortunately, his master also falls in love with the owner of the canine beauty. Soon Anita and Roger get married and Pongo never has to leave Perdita again. As you might expect, after a while Perdita gives birth to beautiful puppies and the whole family revolves around them.
Anita's old classmate Cruella would like them too, but the dogs don't like them at all. They suspect foul play. Cruella, however, is not to be deterred and goes hard after her goal. She wants to make luxurious black and white coats out of dog fur and kidnap the little dogs. Perdita and Pong rebel the animal kingdom to save their children. They experience dramatic moments of danger and suspense, but with the help of their friends, they manage to save the puppies.